产品名称
KILIN Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/100144748
Human Swissprot No.
B2CW77
Human Swissprot Link
https://www.uniprot.org/uniprotkb/B2CW77/entry
免疫原
Synthesized peptide derived from human KILIN AA range: 92-142
特异性
This antibody detects endogenous levels of KILIN at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012],
功能
function:DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single-stranded DNA.,induction:by p53/TP53; direct transcription target of p53/TP53.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
