产品名称
WFKN2 Rabbit Polyclonal Antibody
基因名称
WFIKKN2 GASP1 WFIKKNRP UNQ9235/PRO31996
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/124857
Human Swissprot No.
Q8TEU8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TEU8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/278507
Mouse Swissprot No.
Q7TQN3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TQN3
免疫原
Synthesized peptide derived from human WFKN2 AA range: 506-556
特异性
This antibody detects endogenous levels of WFKN2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008],
组织表达
Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.
功能
function:Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin.,similarity:Belongs to the WFIKKN family.,similarity:Contains 1 BPTI/Kunitz inhibitor domain.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Kazal-like domain.,similarity:Contains 1 NTR domain.,similarity:Contains 1 WAP domain.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,subunit:Interacts with both mature and propeptide myostatin/MSTN.,tissue specificity:Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
