产品名称
GLTL5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/168391
Human Swissprot No.
Q7Z4T8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z4T8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67909
Mouse Swissprot No.
Q9D4M9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D4M9
免疫原
Synthesized peptide derived from human GLTL5 AA range: 79-129
特异性
This antibody detects endogenous levels of GLTL5 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Mainly expressed in testis. Weakly or not expressed in other tissues.
细胞定位
Late endosome membrane ; Single-pass type II membrane protein . Localizes to the juxtanuclear region, possibly the late endosome. Not localized in the Golgi apparatus in round spermatids (By similarity). .
功能
caution:In contrast to other members of the family, it lacks the C-terminal ricin B-type lectin domain, which contributes to the glycopeptide specificity. Its precise function is therefore unsure.,cofactor:Calcium.,cofactor:Manganese.,domain:There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.,function:May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.,online information:GlycoGene database,online information:Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.,tissue specificity:Expressed in testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.