产品名称
TSG10 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/80705
Human Swissprot No.
Q9BZW7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BZW7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/211484
Mouse Swissprot No.
Q6NY15
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6NY15
Rat Gene Link
https://www.uniprot.org/uniprot/252923
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z220
免疫原
Synthesized peptide derived from human TSG10 AA range: 412-462
特异性
This antibody detects endogenous levels of TSG10 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816).
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). .
功能
function:May play a role in the sperm tail fibrous sheath, a major sperm tail structure.,PTM:Appears to be processed in a 27 kDa and a 55 kDa peptide containing respectively the N-terminal and the C-terminal part of the precursor.,similarity:Belongs to the CEP135/TSGA10 family.,subcellular location:The 27 kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail while the 55 kDa peptide localizes to the midpiece.,tissue specificity:Testis specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
