产品名称
GMPPA Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/29926
Human Swissprot No.
Q96IJ6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96IJ6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/69080
Mouse Swissprot No.
Q922H4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q922H4
Rat Gene Link
https://www.uniprot.org/uniprot/501167
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIC1
免疫原
Synthesized peptide derived from human GMPPA AA range: 184-234
特异性
This antibody detects endogenous levels of GMPPA at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. [provided by RefSeq, Jul 2008],
组织表达
Expressed in fibroblasts (at protein level).
细胞定位
Cytoplasm . Myc-tagged GMPPA shows a diffuse cytoplasmic and nuclear pattern in transfected COS-7 cells.
功能
catalytic activity:GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.,pathway:Protein modification; protein glycosylation.,sequence caution:Originally thought to be a fragment.,similarity:Belongs to the transferase hexapeptide repeat family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
