产品名称
KRA59 Rabbit Polyclonal Antibody
基因名称
KRTAP5-9 KAP5.9 KRN1 KRTAP5.9 UHSK1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3846
Human Swissprot No.
P26371
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P26371/entry
免疫原
Synthesized peptide derived from human KRA59 AA range: 9-59
特异性
This antibody detects endogenous levels of KRA59 at Human
宿主
Polyclonal, Rabbit,IgG
组织表达
Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles.
功能
developmental stage:At a late stage of fiber differentiation.,function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 5 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to hair root, not detected in any other tissues. Expressed in cuticle layers of differentiating hair follicles.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
