产品名称
SCLY Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51540
Human Swissprot No.
Q96I15
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96I15/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/50880
Mouse Swissprot No.
Q9JLI6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JLI6
Rat Gene Link
https://www.uniprot.org/uniprot/363285
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q68FT9
免疫原
Synthesized peptide derived from human SCLY AA range: 367-417
特异性
This antibody detects endogenous levels of SCLY at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008],
细胞定位
Cytoplasm, cytosol .
功能
catalytic activity:L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptor.,cofactor:Pyridoxal phosphate.,function:Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.,induction:Up-regulated in acute glomerulonephritis. Regulated by AP-1.,similarity:Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
