产品名称
UBXN1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51035
Human Swissprot No.
Q04323
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q04323/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/225896
Mouse Swissprot No.
Q922Y1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q922Y1
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q499N6
免疫原
Synthesized peptide derived from human UBXN1 AA range: 56-106
特异性
This antibody detects endogenous levels of UBXN1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
功能
function:Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems.,similarity:Contains 1 UBA domain.,similarity:Contains 1 UBX domain.,subunit:Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with HOMER2 (By similarity). Interacts directly with VCP. Binds polyubiquitin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
