产品名称
HEN1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/4807
Human Swissprot No.
Q02575
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q02575/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18071
Mouse Swissprot No.
Q02576
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q02576
免疫原
Synthesized peptide derived from human HEN1 AA range: 73-123
特异性
This antibody detects endogenous levels of HEN1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002],
功能
function:May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
