产品名称
STK19 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/8859
Human Swissprot No.
P49842
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49842/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/54402
Mouse Swissprot No.
Q9JHN8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHN8
免疫原
Synthesized peptide derived from human STK19 AA range: 89-139
特异性
This antibody detects endogenous levels of STK19 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants. [provided by RefSeq, Jul 2008],
组织表达
Monocytes, hepatocytes, epithelial cells, T- and B-lymphocytes.
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Divalent cations. Has a preference for manganese.,function:Seems to be a protein kinase. In vitro it can phosphorylate casein-alpha on serine and threonine residues and histones on serine residues.,similarity:Belongs to the STK19 family.,subunit:The N-terminus interacts with BAG1.,tissue specificity:Monocytes, hepatocytes, epithelial cells, T-and B-lymphocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
