产品名称
SIA7B Rabbit Polyclonal Antibody
基因名称
ST6GALNAC2 SIAT7B SIATL1 STHM
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10610
Human Swissprot No.
Q9UJ37
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UJ37/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20446
Mouse Swissprot No.
P70277
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70277
免疫原
Synthesized peptide derived from human SIA7B AA range: 219-269
特异性
This antibody detects endogenous levels of SIA7B at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).[supplied by OMIM, Mar 2008],
组织表达
Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
catalytic activity:CMP-N-acetylneuraminate + glycano-beta-D-galactosyl-1,3-(N-acetyl-D-galactosaminyl)-glycoprotein = CMP + glycano-beta-D-galactosyl-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein.,online information:GlycoGene database,online information:ST6GalNAc II,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Expressed in skeletal muscle, heart, kidney, placenta, lung and leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
