产品名称
MTNB Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51074
Human Swissprot No.
Q96GX9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96GX9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/56369
Mouse Swissprot No.
Q9WVQ5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVQ5
免疫原
Synthesized peptide derived from human MTNB AA range: 133-183
特异性
This antibody detects endogenous levels of MTNB at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008],
组织表达
Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.
功能
cofactor:Binds 1 zinc ion per subunit .,function:Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.,similarity:Belongs to the aldolase class II family. APIP subfamily.,subunit:Interacts with APAF1.,tissue specificity:Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
