产品名称
ACTT1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/139741
Human Swissprot No.
Q8TDG2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TDG2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/73360
Mouse Swissprot No.
Q9D9J3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D9J3
Rat Gene Link
https://www.uniprot.org/uniprot/302796
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIK1
免疫原
Synthesized peptide derived from human ACTT1 AA range: 241-291
特异性
This antibody detects endogenous levels of ACTT1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010],
组织表达
In skin, expressed in the basal, spinous and granular layers of the epidermis. Also expressed in hair follicles, sebaceaous glands, eccrine sweat glands and semen.
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm . Nucleus . Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway. .
功能
similarity:Belongs to the actin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
