产品名称
MS4A7 Rabbit Polyclonal Antibody
基因名称
MS4A7 4SPAN2 CD20L4 CFFM4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/58475
Human Swissprot No.
Q9GZW8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9GZW8/entry
免疫原
Synthesized peptide derived from human MS4A7 AA range: 3-53
特异性
This antibody detects endogenous levels of MS4A7 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:May be involved in signal transduction as a component of a multimeric receptor complex.,similarity:Belongs to the MS4A family.,tissue specificity:Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
