产品名称
KIF1C Rabbit Polyclonal Antibody
蛋白名称
Kinesin-like protein KIF1C
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O43896
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O43896/entry
Mouse Swissprot No.
O35071
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35071
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941O35787
免疫原
Synthesized peptide derived from human protein . at AA range: 1110-1190
特异性
KIF1C Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
kinesin family member 1C(KIF1C) Homo sapiens The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014],
组织表达
Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.
细胞定位
Cytoplasm, cytoskeleton .
功能
function:Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the kinesin-like protein family. Unc-104 subfamily.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Monomer .,tissue specificity:Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
