产品名称
EHBP1 Rabbit Polyclonal Antibody
基因名称
EHBP1 KIAA0903 NACSIN
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23301
Human Swissprot No.
Q8NDI1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NDI1/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/216565
Mouse Swissprot No.
Q69ZW3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q69ZW3
免疫原
Synthesized peptide derived from human EHBP1 AA range: 364-414
特异性
This antibody detects endogenous levels of EHBP1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
细胞定位
Cytoplasm . Membrane . Endosome . Mostly found in cytosol and plasma membrane.
功能
disease:A genetic variation in EHBP1 is associated with susceptibility to hereditary prostate cancer type 12 (HPC12) [MIM:611868].,function:May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 CH (calponin-homology) domain.,subcellular location:Mostly found in cytosol and plasma membrane.,subunit:Interacts with EHD2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
