产品名称
RGL3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/57139
Human Swissprot No.
Q3MIN7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q3MIN7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/71746
Mouse Swissprot No.
Q3UYI5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UYI5
免疫原
Synthesized peptide derived from human RGL3 AA range: 601-651
特异性
This antibody detects endogenous levels of RGL3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
功能
domain:The Ras-associating domain plays a central role in the activation of Ral-A GDP/GTP exchange activity.,function:Guanine nucleotide exchange factor (GEF) for Ral-A. Potential effector of GTPase HRas and Ras-related protein M-Ras. Negatively regulates Elk-1-dependent gene induction downstream of HRas and MEKK1.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subunit:Interacts with GTP-bound forms of RIT1, HRAS and MRAS.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.