产品名称
TSSP Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10279
Human Swissprot No.
Q9NQE7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQE7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/54373
Mouse Swissprot No.
Q9QXE5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QXE5
免疫原
Synthesized peptide derived from human TSSP AA range: 50-100
特异性
This antibody detects endogenous levels of TSSP at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008],
组织表达
Expressed predominantly in cortical thymic epithelial cells.
细胞定位
Cytoplasmic vesicle. Vesicular, either lysosomal or endosomal.
功能
developmental stage:Expressed in fetal thymus.,function:Protease that may play a role in T-cell development.,similarity:Belongs to the peptidase S28 family.,subcellular location:Vesicular, either lysosomal or endosomal.,tissue specificity:Expressed predominantly in cortical thymic epithelial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
