产品名称
SPRE3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/399473
Human Swissprot No.
Q2MJR0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2MJR0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/101809
Mouse Swissprot No.
Q6P6N5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P6N5
免疫原
Synthesized peptide derived from human SPRE3 AA range: 311-361
特异性
This antibody detects endogenous levels of SPRE3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
细胞定位
Cell membrane ; Peripheral membrane protein .
功能
function:Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.,PTM:Phosphorylated on tyrosine.,similarity:Contains 1 SPR (sprouty) domain.,similarity:Contains 1 WH1 domain.,subunit:Interacts with Ras.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
