产品名称
S61A2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55176
Human Swissprot No.
Q9H9S3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H9S3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/57743
Mouse Swissprot No.
Q9JLR1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JLR1
免疫原
Synthesized peptide derived from human S61A2 AA range: 318-368
特异性
This antibody detects endogenous levels of S61A2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
function:Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins.,similarity:Belongs to the secY/SEC61-alpha family.,subunit:Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
