产品名称
PNMT Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5409
Human Swissprot No.
P11086
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P11086/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/18948
Mouse Swissprot No.
P40935
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P40935
Rat Gene Link
https://www.uniprot.org/uniprot/24661
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P10937
免疫原
Synthesized peptide derived from human PNMT AA range: 96-146
特异性
This antibody detects endogenous levels of PNMT at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],
功能
catalytic activity:S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.,function:Converts noradrenaline to adrenaline.,pathway:Catecholamine biosynthesis; epinephrine biosynthesis; epinephrine from norepinephrine: step 1/1.,similarity:Belongs to the NNMT/PNMT/TEMT family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
