产品名称
SNX33 Rabbit Polyclonal Antibody
基因名称
SNX33 SH3PX3 SH3PXD3C SNX30
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/257364
Human Swissprot No.
Q8WV41
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WV41/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/235406
Mouse Swissprot No.
Q4VAA7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q4VAA7
免疫原
Synthesized peptide derived from human SNX33 AA range: 55-105
特异性
This antibody detects endogenous levels of SNX33 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is involved in cytoskeletal reorganization, vesicle trafficking, endocytosis, and mitosis. The encoded protein is essential for the creation of the cleavage furrow during mitosis and for completion of mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
组织表达
Detected in heart and pancreas.
细胞定位
Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Primarily cytosolic, but a minor proportion is membrane-bound (PubMed:18353773). Not associated with membranes (PubMed:21048941). .
功能
similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ADAM15.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
