产品名称
AEBP2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/121536
Human Swissprot No.
Q6ZN18
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZN18/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/11569
Mouse Swissprot No.
Q9Z248
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z248
免疫原
Synthesized peptide derived from human AEBP2 AA range: 155-205
特异性
This antibody detects endogenous levels of AEBP2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
细胞定位
Nucleus . Localizes to chromatin as part of the PRC2 complex. .
功能
function:DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.,sequence caution:Translated as Gln.,similarity:Belongs to the AEBP2/jing C2H2-type zinc-finger family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Self-associates. Interacts with EED, EZH2, RBBP4 and SUZ12. Component of the PRC2/EED-EZH1 complex, which includes EED, EZH1, SUZ12, RBBP4 and AEBP2 (By similarity). May also interact with RBBP7.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
