产品名称
STX3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6809
Human Swissprot No.
Q13277
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13277/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20908
Mouse Swissprot No.
Q64704
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q64704
Rat Gene Link
https://www.uniprot.org/uniprot/81802
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q08849
免疫原
Synthesized peptide derived from human STX3 AA range: 6-56
特异性
This antibody detects endogenous levels of STX3 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
组织表达
[Isoform A]: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. ; [Isoform B]: Expressed only in the retina. ; [Isoform 3]: Ubiquitously expressed.
细胞定位
[Isoform A]: Apical cell membrane ; Single-pass type IV membrane protein . Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors. .; [Isoform 3]: Nucleus .
功能
function:Potentially involved in docking of synaptic vesicles at presynaptic active zones.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
