产品名称
GGT6 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/124975
Human Swissprot No.
Q6P531
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P531/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/71522
Mouse Swissprot No.
Q6PDE7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PDE7
Rat Gene Link
https://www.uniprot.org/uniprot/408206
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IE08
免疫原
Synthesized peptide derived from human GGT6 AA range: 254-304
特异性
This antibody detects endogenous levels of GGT6 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008],
细胞定位
Membrane ; Single-pass type II membrane protein .
功能
catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,function:Cleaves glutathione conjugates.,pathway:Sulfur metabolism; glutathione metabolism.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
