产品名称
DLGP4 Rabbit Polyclonal Antibody
基因名称
DLGAP4 DAP4 KIAA0964 SAPAP4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/22839
Human Swissprot No.
Q9Y2H0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y2H0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/228836
Mouse Swissprot No.
B1AZP2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/B1AZP2
Rat Gene Link
https://www.uniprot.org/uniprot/286930
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P97839
免疫原
Synthesized peptide derived from human DLGP4 AA range: 220-270
特异性
This antibody detects endogenous levels of DLGP4 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Peripheral membrane protein .
功能
function:May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.,similarity:Belongs to the SAPAP family.,subunit:Interacts with DLG1 and DLG4/PSD-95.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
