产品名称
CBPC5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/60509
Human Swissprot No.
Q8NDL9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NDL9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/231093
Mouse Swissprot No.
Q09M02
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q09M02
Rat Gene Link
https://www.uniprot.org/uniprot/362710
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B2GV17
免疫原
Synthesized peptide derived from human CBPC5 AA range: 499-549
特异性
This antibody detects endogenous levels of CBPC5 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a metallocarboxypeptidase involved in protein deglutamylation and a member of the peptidase M14 family of proteins. The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates. This deglutamylase activity may be important in antiviral immunity. Mutations in this gene are associated with retinitis pigmentosa. [provided by RefSeq, Jul 2016],
细胞定位
Cytoplasm, cytosol . Nucleus . Cytoplasm, cytoskeleton, spindle . Midbody . Mainly cytoplasmic. Slight accumulation in the nucleus is observed (By similarity). Colocalizes with alpha-tubulin in the mitotic spindle and with midbody microtubules in the intercellular bridges formed during cytokinesis. .
功能
similarity:Belongs to the peptidase M14 family.,tissue specificity:Expressed in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
