产品名称
RUN3B Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/154661
Human Swissprot No.
Q96NL0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96NL0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/242819
Mouse Swissprot No.
Q6PDC0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PDC0
Rat Gene Link
https://www.uniprot.org/uniprot/688590
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q3B7K9
免疫原
Synthesized peptide derived from human RUN3B AA range: 79-129
特异性
This antibody detects endogenous levels of RUN3B at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Isoform 2 is expressed at high levels in brain, thymus, ovary, testis, leukocyte, liver, small intestine and prostate. Isoform 1 is expressed in the brain, testis and adrenal gland. It is activated in tumorigenic breast cancer cell lines and in the primary tumor of breast cancer patients. Activation also correlates with metastatic lymph node invasion and can be detected in metastatic epithelial cells from the lymph nodes and in the bone marrow of patients.
功能
similarity:Belongs to the RUNDC3 family.,similarity:Contains 1 RUN domain.,subunit:Interacts with RAP2A.,tissue specificity:Isoform 2 is expressed at high levels in brain, thymus, ovary, testis, leukocyte, liver, small intestine and prostate. Isoform 1 is expressed in the brain, testis and adrenal gland. It is activated in tumorigenic breast cancer cell lines and in the primary tumor of breast cancer patients. Activation also correlates with metastatic lymph node invasion and can be detected in metastatic epithelial cells from the lymph nodes and in the bone marrow of patients.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
