产品名称
TM138 Rabbit Polyclonal Antibody
基因名称
TMEM138 HSPC196 HSPC198
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51524
Human Swissprot No.
Q9NPI0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NPI0/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/72982
Mouse Swissprot No.
Q9D6G5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D6G5
Rat Gene Link
https://www.uniprot.org/uniprot/361728
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B1WBM3
免疫原
Synthesized peptide derived from human TM138 AA range: 75-125
特异性
This antibody detects endogenous levels of TM138 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],
细胞定位
Vacuole membrane ; Multi-pass membrane protein . Cell projection, cilium . Localizes to vesicles en route to the base of cilium.
功能
similarity:Belongs to the TMEM138 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
