产品名称
UBIP1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/7342
Human Swissprot No.
Q9NZI7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NZI7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/22221
Mouse Swissprot No.
Q811S7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q811S7
免疫原
Synthesized peptide derived from human UBIP1 AA range: 264-314
特异性
This antibody detects endogenous levels of UBIP1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines.
功能
function:Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.,induction:Induced by HIV-1 infection of lymphocytes.,similarity:Belongs to the grh/CP2 family. CP2 subfamily.,subunit:Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.,tissue specificity:Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
