产品名称
ARPC5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10092
Human Swissprot No.
O15511
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15511/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67771
Mouse Swissprot No.
Q9CPW4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CPW4
Rat Gene Link
https://www.uniprot.org/uniprot/360854
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KLF8
免疫原
Synthesized peptide derived from human ARPC5 AA range: 58-108
特异性
This antibody detects endogenous levels of ARPC5 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
细胞定位
Cytoplasm, cytoskeleton . Cell projection . Nucleus .
功能
function:Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.,similarity:Belongs to the ARPC5 family.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
