产品名称
PRAP1 Rabbit Polyclonal Antibody
基因名称
PRAP1 UPA UNQ608/PRO1195
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/118471
Human Swissprot No.
Q96NZ9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96NZ9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/22264
Mouse Swissprot No.
Q80XD8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80XD8
Rat Gene Link
https://www.uniprot.org/uniprot/60574
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ES75
免疫原
Synthesized peptide derived from human PRAP1 AA range: 84-134
特异性
This antibody detects endogenous levels of PRAP1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Highly expressed in the intestinal epithelial cells (at protein level) (PubMed:32629119). Abundantly expressed in the epithelial cells of the liver, kidney and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues. Expressed in epididymis (at protein level).
细胞定位
Secreted . Endoplasmic reticulum .
功能
function:May play an important role in maintaining normal growth homeostasis in epithelial cells.,induction:Up-regulated by butyrate, trichostatin A and 5'-aza-2' deoxycytidine.,tissue specificity:Abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
