产品名称
SPS1 Rabbit Polyclonal Antibody
基因名称
SEPHS1 SELD SPS SPS1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/22929
Human Swissprot No.
P49903
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49903/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/109079
Mouse Swissprot No.
Q8BH69
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BH69
免疫原
Synthesized peptide derived from human SPS1 AA range: 323-373
特异性
This antibody detects endogenous levels of SPS1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010],
组织表达
[Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases. ; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases. ; [Isoform 3]: Gradually expressed during the cell cycle until S phase and then decreases.
细胞定位
[Isoform 1]: Cell membrane ; Peripheral membrane protein . Nucleus membrane ; Peripheral membrane protein .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm .
功能
catalytic activity:ATP + selenide + H(2)O = AMP + selenophosphate + phosphate.,caution:The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is proven, it is possible Cys-31 is the active site.,function:Synthesizes selenophosphate from selenide and ATP.,similarity:Belongs to the selenophosphate synthetase 1 family. Class II subfamily.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
