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现货抗体产品库

PRCC Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN3960
产品名称
PRCC Rabbit Polyclonal Antibody
类别
常规抗体
基因名称
PRCC TPRC
蛋白名称
PRCC
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
5546
Human Gene Link
https://www.uniprot.org/uniprot/5546
Human Swissprot No.
Q92733
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92733/entry
免疫原
Synthesized peptide derived from human PRCC AA range: 74-124
特异性
This antibody detects endogenous levels of PRCC at Human
稀释度
WB 1:500-2000
参考分子量
54kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010],
组织表达
Ubiquitous in fetal and adult tissues.
细胞定位
Nucleus .
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,disease:A chromosomal aberration involving PRCC may be a cause of papillary renal cell carcinoma (PRCC) [MIM:605074]. Translocation t(X;1)(p11.2;q21.2) with TFE3.,tissue specificity:Ubiquitous in fetal and adult tissues.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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