产品名称
DJC13 Rabbit Polyclonal Antibody
基因名称
DNAJC13 KIAA0678 RME8
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23317
Human Swissprot No.
O75165
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75165/entry
免疫原
Synthesized peptide derived from human DJC13 AA range: 1576-1626
特异性
This antibody detects endogenous levels of DJC13 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016],
细胞定位
Early endosome . Early endosome membrane ; Peripheral membrane protein . Endosome membrane .
功能
sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 748.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Translated as Glu.,similarity:Contains 1 J domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.