产品名称
INCA1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/388324
Human Swissprot No.
Q0VD86
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q0VD86/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/103844
Mouse Swissprot No.
Q6PKN7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PKN7
免疫原
Synthesized peptide derived from human INCA1 AA range: 10-60
特异性
This antibody detects endogenous levels of INCA1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors (PubMed:15159402). Down-regulated in bone marrow cells in acute myeloid and lymphoid leukemia patients as compared with normal bone marrow cells (PubMed:21540187).
细胞定位
Nucleus . Cytoplasm .
功能
PTM:Phosphorylated when part of a complex with CCNA1 and CDK2. Strongly phosphorylated by CDK2 on its C-terminal region spanning amino acid 149-221. Less intensively phosphorylated by CDK2 on its first 75 amino acid residues.,similarity:Belongs to the INCA family.,subunit:Interacts with CCNA1. Identified in a complex with CCNA1 and CDK2.,tissue specificity:Detected in testis, and at lower levels in ovary. Detected at very low levels in testis tumors.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
