产品名称
LAMP5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/24141
Human Swissprot No.
Q9UJQ1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UJQ1/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/76161
Mouse Swissprot No.
Q9D387
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D387
Rat Gene Link
https://www.uniprot.org/uniprot/362220
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5PPI4
免疫原
Synthesized peptide derived from human LAMP5 AA range: 143-193
特异性
This antibody detects endogenous levels of LAMP5 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in plasmocytoid dendritic cells. Expressed in suprabasal skin keratinocytes and squamous cells (at protein level). Expressed in the brain and weakly in spleen and skin. Expressed in plasmocytoid dendritic cells.
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle membrane ; Single-pass type I membrane protein . Cell projection, dendrite . Cell projection, growth cone membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . Recycling endosome . Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (By similarity). Colocalizes with UNC93B1 in large endosomal intracellular vesicles (PubMed:21642595). Accumulates in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) before its disappearance upon activation by CpG dinucleotides (PubMed:21642595). Associates with cortical membranes (PubMed:21642595). Localizes mostly in cytoplasmic vesicles of neuronal cell body (By similarity). Localizes to synaptic vesicles in a subset of GABAergic neurons (By similarity). .
功能
similarity:Belongs to the LAMP family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
