产品名称
SSRB Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6746
Human Swissprot No.
P43308
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P43308/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/66256
Mouse Swissprot No.
Q9CPW5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CPW5
免疫原
Synthesized peptide derived from human SSRB AA range: 107-157
特异性
This antibody detects endogenous levels of SSRB at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
功能
function:TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.,similarity:Belongs to the TRAP-beta family.,subunit:Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with TMEM173/STING.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
