产品名称
PPAC2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/403313
Human Swissprot No.
Q8IY26
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IY26/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74411
Mouse Swissprot No.
Q9D4F2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D4F2
Rat Gene Link
https://www.uniprot.org/uniprot/619549
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q66H88
免疫原
Synthesized peptide derived from human PPAC2 AA range: 145-195
特异性
This antibody detects endogenous levels of PPAC2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Nucleus envelope . Nucleus inner membrane .
功能
function:Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.,similarity:Belongs to the PA-phosphatase related phosphoesterase family.,tissue specificity:Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.