产品名称
Flotillin-1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Swissprot No.
O75955
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75955/entry
免疫原
Synthesized peptide derived from human Flotillin-1
特异性
This antibody detects endogenous levels of human Flotillin-1
稀释度
WB 1:500-2000, ELISA(peptide)1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
组织表达
Adipose tissue,Adrenal gland,Lung,Peripheral blood leukocyte,Umbilical cord blood,
细胞定位
Cell membrane; Peripheral membrane protein . Endosome . Membrane, caveola ; Peripheral membrane protein . Melanosome . Membrane raft . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Membrane-associated protein of caveola (By similarity). .
功能
function:May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.,similarity:Belongs to the band 7/mec-2 family. Flotillin subfamily.,subcellular location:Membrane-associated protein of caveolae. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
