产品名称
Keratin 77 Rabbit Polyclonal Antibody
别名
Keratin, type II cytoskeletal 1b (Cytokeratin-1B;CK-1B;Keratin-77;K77;Type-II keratin Kb39)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Swissprot No.
Q7Z794
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z794/entry
免疫原
Synthesized peptide derived from human Keratin 77
特异性
This antibody detects endogenous levels of human Keratin 77
稀释度
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in the skin and eccrine sweat glands. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009],
组织表达
Expressed exclusively in skin.
细胞定位
cytoskeleton,intermediate filament,keratin filament,extracellular exosome,
功能
miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Undergoes deimination of some arginine residues (citrullination).,similarity:Belongs to the intermediate filament family.,tissue specificity:Expressed exclusively in skin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
