产品名称
Secretogranin-1 Rabbit Polyclonal Antibody
别名
Secretogranin-1 (Chromogranin-B;CgB;Secretogranin I;SgI) [Cleaved into: GAWK peptide; CCB peptide]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Swissprot No.
P05060
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P05060/entry
免疫原
Synthesized peptide derived from human Secretogranin-1
特异性
This antibody detects endogenous levels of human Secretogranin-1
稀释度
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009],
组织表达
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.
细胞定位
Secreted. Neuroendocrine and endocrine secretory granules.
功能
function:Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,PTM:Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
