产品名称
TIG1 Rabbit Polyclonal Antibody
别名
Retinoic acid receptor responder protein 1 (RAR-responsive protein TIG1;Tazarotene-induced gene 1 protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Swissprot No.
P49788
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49788/entry
免疫原
Synthesized peptide derived from human TIG1
特异性
This antibody detects endogenous levels of human TIG1
稀释度
IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Single-pass type III membrane protein .
功能
induction:By tazarotene and by all the retinoic acid receptors tested.,similarity:Belongs to the protease inhibitor I47 (latexin) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
