产品名称
IFI30 Rabbit Polyclonal Antibody
别名
Gamma-interferon-inducible lysosomal thiol reductase (EC 1.8.-.-) (Gamma-interferon-inducible protein IP-30) (Legumaturain)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.06% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10437
Human Swissprot No.
P13284
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P13284/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/65972
Mouse Swissprot No.
Q9ESY9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ESY9
Rat Gene Link
https://www.uniprot.org/uniprot/290644
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q499T2
免疫原
Synthesized peptide derived from human IFI30 AA range: 3-53
特异性
This antibody detects endogenous levels of IFI30 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008],
细胞定位
Secreted . Lysosome .
功能
function:Cleaves disulfide bonds in proteins by reduction. May facilitate the complete unfolding of proteins destined for lysosomal degradation. May be involved in MHC class II-restricted antigen processing.,induction:Expressed constitutively in antigen-presenting cells and induced by IFN-gamma in other cell types.,PTM:N-glycosylated. Sugar chains contain mannose-6-phosphate.,similarity:Belongs to the GILT family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
