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α-tubulin(Acetyl Lys40)(5H5)Mouse Monoclonal Antibody

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产品基本信息

产品货号
BD-PM3585
产品名称
α-tubulin(Acetyl Lys40)(5H5)Mouse Monoclonal Antibody
别名
Tubulin alpha-1B chain (Alpha-tubulin ubiquitous;Tubulin K-alpha-1;Tubulin alpha-ubiquitous chain)
类别
常规抗体
基因名称
TUBA1B
蛋白名称
Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain)
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
7277
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7277
Human Swissprot No.
P68363
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P68363/entry
Mouse Swissprot No.
P05213
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P05213
Rat Swissprot No.
Q6P9V9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6P9V9
免疫原
Synthetic Peptide of α-tubulin (Acetyl Lys40)
特异性
α-tubulin (Acetyl Lys40) protein detects endogenous levels of α-tubulin (Acetyl Lys40)
稀释度
WB 1:1000-2000, IHC 1:100-200. IF 1:50-200
预测分子量
52kD
运输及保存条件
-20°C/1 year
宿主
Monoclonal, Mouse
背景介绍
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
组织表达
Brain,Cajal-Retzius cell,Colon,Embryonic kidney,Eye,Fetal brain cortex,Keratinocyte
细胞定位
Cytoplasm, cytoskeleton.
信号通路
Gap junction;Pathogenic Escherichia coli infection;
功能
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
期货
现货
纯化
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Western blot analysis of extracts from Hela cells, untreated (-) or treated with TSA (1μM, 18 hr; +), using Acetyl- a-tubulin(Lys40) Mouse mAb 1:2000.

Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using a-tubulin(Acetyl Lys40) Mouse mAb diluted at 1:200.

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