产品名称
ACO2 Rabbit Polyclonal Antibody
别名
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)
反应种属
Human,Mouse,Rat,Canine
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50
Human Swissprot No.
Q99798
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q99798/entry
Mouse Swissprot No.
Q99KI0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99KI0
免疫原
Synthesized peptide derived from human ACO2. at AA range: 421-470
特异性
ACO2 Polyclonal Antibody detects endogenous levels of ACO2
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000.Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008],
组织表达
Brain,Cajal-Retzius cell,Fetal brain cortex,Skeletal muscle,Uterus,
信号通路
Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;
功能
catalytic activity:Citrate = isocitrate.,cofactor:Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive enzyme.,online information:Aconitase entry,pathway:Carbohydrate metabolism; tricarboxylic acid cycle.,similarity:Belongs to the aconitase/IPM isomerase family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
