产品名称
OASL Rabbit Polyclonal Antibody
别名
2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8638
Human Swissprot No.
Q15646
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15646/entry
免疫原
Synthesized peptide derived from human OASL. at AA range: 1-50
特异性
OASL Polyclonal Antibody detects endogenous levels of OASL
稀释度
WB 1:500-2000, ELISA 1:10000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.,
组织表达
Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
细胞定位
[Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.
功能
caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
