产品名称
AFG3L2 Rabbit Polyclonal Antibody
别名
AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10939
Human Swissprot No.
Q9Y4W6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y4W6/entry
Mouse Swissprot No.
Q8JZQ2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8JZQ2
免疫原
Synthesized peptide derived from human AFG3L2. at AA range: 744-793
特异性
AFG3L2 Polyclonal Antibody detects endogenous levels of AFG3L2
稀释度
WB 1:500-2000, ELISA 1:10000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitous. Highly expressed in the cerebellar Purkinje cells.
细胞定位
Mitochondrion . Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
cofactor:Binds 1 zinc ion per subunit .,function:Putative ATP-dependent protease.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
