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GCM2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT6090
产品名称
GCM2 Rabbit Polyclonal Antibody
别名
Chorion-specific transcription factor GCMb (hGCMb) (GCM motif protein 2) (Glial cells missing homolog 2)
类别
常规抗体
基因名称
GCM2
蛋白名称
GCM2
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
9247
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9247
Human Swissprot No.
O75603
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75603/entry
Mouse Gene ID
107889
Mouse Swissprot No.
O09102
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O09102
免疫原
Synthesized peptide derived from human GCM2. at AA range: 21-70
特异性
GCM2 Polyclonal Antibody detects endogenous levels of GCM2
稀释度
WB 1:500-2000, ELISA 1:10000-20000
预测分子量
56kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008],
组织表达
Brain,Fetal brain,
细胞定位
Nucleus .
功能
function:Probable transcriptional regulator.,similarity:Contains 1 GCM DNA-binding domain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of 293T cells using primary antibody diluted at 1:500(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)

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