产品名称
GCM2 Rabbit Polyclonal Antibody
别名
Chorion-specific transcription factor GCMb (hGCMb) (GCM motif protein 2) (Glial cells missing homolog 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9247
Human Swissprot No.
O75603
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75603/entry
Mouse Swissprot No.
O09102
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O09102
免疫原
Synthesized peptide derived from human GCM2. at AA range: 21-70
特异性
GCM2 Polyclonal Antibody detects endogenous levels of GCM2
稀释度
WB 1:500-2000, ELISA 1:10000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008],
功能
function:Probable transcriptional regulator.,similarity:Contains 1 GCM DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.