产品名称
AVPR1A Rabbit Polyclonal Antibody
别名
Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=552
Human Swissprot No.
P37288
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P37288/entry
Mouse Swissprot No.
Q62463
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62463
免疫原
Synthesized peptide derived from human AVPR1A. at AA range: 11-60
特异性
AVPR1A Polyclonal Antibody detects endogenous levels of AVPR1A
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Calcium;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction;
功能
function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.,miscellaneous:Differences in regional receptor expression in the brain as well as differences in social behavior may result from a highly variable repetitive sequence in the 5' flanking region of AVPR1A. One such allelic variant has been linked to autism.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
